Several studies have been carried out to compare the results obtained with the ChemMatrix® vs. Polystyrene resins for the synthesis of difficult peptides on Fmoc SPPS.  

Different peptides sequences that are known to be difficult to synthesize due to their lengths, complexity and/or hydrophobicity have been identified. Peptides synthesis were performed on ChemMatrix® and Polystyrene resins ans the results are shown below.

	Peptide	Length	Category
	β-Amyloid 1-42	42 amino acids	Complex
	HIV-1 Protease	99 amino acids	Long
	Bacuma	38 amino acids	Long
	H-(Ala)10-Val-OH	11 amino acids	Hydrophobic
	Rantes	68 amino acids	Long
	Poly Arg(21)	21 amino acids	Complex

To see more results visit our references page (a non-exhaustive list of publication)