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For peptides acid, we recommend using the HMPB-ChemMatrix® as this resin will provide high crude purity.

According to TFA Cleavage conditions, 95% TFA or 1% TFA, you can obtain peptide acids or protected peptide fragments, respectively.

HMPB-ChemMatrix® resins are offered preloaded will all 20 natural amino acids.  Other amino acids can be preloaded on special request. 

Category: Peptide acid resin
Synthesis protocol: Click here for synthesis protocols
Cleavage conditions:  TFA / H2O / Et3SiH (95/2,5/2,5)
Loading average:

0.40-0.70 mmol/g (HMPB-ChemMatrix®)
0.30-0.65 mmol/g  (Preloaded HMPB-ChemMatrix®)

Bead size: 100-200 mesh dry
Swelling: Click here for swelling graphic

Important notice: Please take note that the ChemMatrix® resins swell more than polystyrene resins, especially at the cleavage step where 95% TFA is used.  Make sure to have a reaction vessel that will allow a higher volume to avoid overflowing.  At the cleavage step, make sure to use enough TFA to allow the ChemMatrix® resin to be properly swollen. 
For microwave conditions, you may need to adapt your heating conditions (please check with your equipment supplier).
Storage: +4°C , under dry and inert atmosphere

ChemMatrix® Resins Product number  Quantities 
HMPB-ChemMatrix ® 1031190  (7-820-1310) 50g100g Order
H-Ala-HMPB-ChemMatrix® 1040355  (CFL-820-0101) 25g50g Order
H-Arg(Pbf)-HMPB-ChemMatrix® 1040357  (CFL-820-0201) 25g50g Order
H-Asn(Trt)-HMPB-ChemMatrix® 1040350  (CFL-820-0301) 25g50g Order
H-Asp(OtBu)-HMPB-ChemMatrix® 1040358  (CFL-820-0401) 25g50g Order
H-Cys(Trt)-HMPB-ChemMatrix® 1040359  (CFL-820-0501) 25g50g Order
H-Gln(Trt)-HMPB-ChemMatrix® 1040360  (CFL-820-0601) 25g50g Order
H-Glu(OtBu)-HMPB-ChemMatrix® 1040361  (CFL-820-0701) 25g50g Order
H-Gly-HMPB-ChemMatrix® 1040351  (CFL-820-0801) 25g50g Order
H-His(Trt)-HMPB-ChemMatrix® 1040362  (CFL-820-0901) 25g50g Order
H-Ile-HMPB-ChemMatrix® 1040363  (CFL-820-1001) 25g50g Order
H-Leu-HMPB-ChemMatrix® 1040354  (CFL-820-1101) 25g50g Order
H-Lys(Boc)-HMPB-ChemMatrix® 1040364  (CFL-820-1201) 25g50g Order
H-Met-HMPB-ChemMatrix® 1040382  (CFL-820-1301) 25g50g Order
H-Phe-HMPB-ChemMatrix® 1040365  (CFL-820-1401) 25g50g Order
H-Pro-HMPB-ChemMatrix® 1649  (CFL-820-1501) 25g50g Order
H-Ser(OtBu)-HMPB-ChemMatrix® 1040356  (CFL-820-1601) 25g50g Order
H-Thr(OtBu)-HMPB-ChemMatrix® 1040366  (CFL-820-1701) 25g50g Order
H-Trp(Boc)-HMPB-ChemMatrix® 1040367  (CFL-820-1801) 25g50g Order
H-Tyr(OtBu)-HMPB-ChemMatrix® 1040352  (CFL-820-1901) 25g50g Order
H-Val-HMPB-ChemMatrix® 1040368  (CFL-820-2001) 25g50g Order

For pricing on bulk quantities, please contact your sales representative at:
North America: 
Other countries:

For technical support on our ChemMatrix® resins, please contact us at:

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